What must be done with an inhaler before use?

Shaking an inhaler before use is essential for ensuring that the medication is well-mixed and delivered properly when the inhaler is used. Many inhalers contain a propellant that can separate from the medication, and shaking distributes the medication evenly, allowing for a consistent dose with each use. This step is particularly critical for inhalers that deliver aerosolized medication, as it helps avoid clogs and ensures the correct amount of medication reaches the lungs.

Cleaning, priming, or refrigerating inhalers, while important in different contexts, do not serve the same immediate purpose as shaking. Cleaning can help maintain the device's functionality and hygiene, priming is sometimes necessary for certain types of inhalers to ensure correct dosing upon initial use or after periods of non-use, and refrigeration can potentially damage some inhaler formulations. However, shaking directly affects the usability and effectiveness of the inhaler at the moment of administration, making it the crucial step before use.