How does the body metabolize medications?

The body metabolizes medications primarily through liver enzymes that chemically alter drugs for elimination. This process, known as drug metabolism, takes place mainly in the liver, where enzymes modify the chemical structure of medications. This modification can transform drugs into active metabolites or facilitate their conversion into non-toxic forms that are easier for the body to eliminate through urine or feces.

The liver plays a critical role in this process due to its rich supply of blood and the presence of various enzymes that can oxidize, reduce, hydrolyze, or conjugate drugs. This enzymatic activity not only helps in breaking down medications but also influences the duration and intensity of their effects on the body. The metabolic processes can also determine a drug's bioavailability and efficacy.

While other tissues and organs may play a role in the metabolism or excretion of certain substances, the liver is the primary site for drug metabolism in the body, making this option the most accurate depiction of how the body handles medications.